Sell Nisin

CAS: 1414-45-5

Nisin is a polypeptide consisting of 34 amino acid residues with a molecular weight of approximately 3,500 Daltons. Its molecular structure is composed of five rings (A to E) and three methyl-lanthionine (MeLan) bridges. The rings are formed by amino acids with unusual modifications, including dehydroalanine, dehydrobutyrine, and lanthionine. The MeLan bridges are formed by the addition of a sulfur atom to two neighboring amino acids, creating a stable and rigid structure. These unique structural features of nisin contribute to its antimicrobial properties and stability in various conditions.

Nisin is effective in inhibiting the growth and reproduction of many Gram-positive bacteria that cause food spoilage, particularly heat-resistant Bacillus and Clostridium botulinum. It also has a strong inhibitory effect on the spores produced by these bacteria.